Lpg0393 of Legionella pneumophila Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22
Identifieur interne : 000080 ( Main/Exploration ); précédent : 000079; suivant : 000081Lpg0393 of Legionella pneumophila Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22
Auteurs : Young-Sik Sohn [Corée du Sud] ; Ho-Chul Shin [Corée du Sud] ; Wei Sun Park [Corée du Sud] ; Jianning Ge [États-Unis] ; Chan-Hee Kim [Corée du Sud] ; Bok Luel Lee [Corée du Sud] ; Won Do Heo [Corée du Sud] ; Jae U. Jung [États-Unis] ; Daniel John Rigden [Royaume-Uni] ; Byung-Ha Oh [Corée du Sud]Source :
- PLoS ONE [ 1932-6203 ] ; 2015.
Abstract
Url:
DOI: 10.1371/journal.pone.0118683
PubMed: 25821953
PubMed Central: 4379102
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000026
- to stream Pmc, to step Curation: 000026
- to stream Pmc, to step Checkpoint: 000073
- to stream Ncbi, to step Merge: 000377
- to stream Ncbi, to step Curation: 000377
- to stream Ncbi, to step Checkpoint: 000377
- to stream Main, to step Merge: 000080
- to stream Main, to step Curation: 000080
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Lpg0393 of <italic>Legionella pneumophila</italic>
Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22</title>
<author><name sortKey="Sohn, Young Sik" sort="Sohn, Young Sik" uniqKey="Sohn Y" first="Young-Sik" last="Sohn">Young-Sik Sohn</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shin, Ho Chul" sort="Shin, Ho Chul" uniqKey="Shin H" first="Ho-Chul" last="Shin">Ho-Chul Shin</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-600, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-600</wicri:regionArea>
<wicri:noRegion>305-600</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Park, Wei Sun" sort="Park, Wei Sun" uniqKey="Park W" first="Wei Sun" last="Park">Wei Sun Park</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ge, Jianning" sort="Ge, Jianning" uniqKey="Ge J" first="Jianning" last="Ge">Jianning Ge</name>
<affiliation wicri:level="4"><nlm:aff id="aff003"><addr-line>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
<settlement type="city">Los Angeles</settlement>
</placeName>
<orgName type="university">Université de Californie du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Kim, Chan Hee" sort="Kim, Chan Hee" uniqKey="Kim C" first="Chan-Hee" last="Kim">Chan-Hee Kim</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735</wicri:regionArea>
<wicri:noRegion>609-735</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lee, Bok Luel" sort="Lee, Bok Luel" uniqKey="Lee B" first="Bok Luel" last="Lee">Bok Luel Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735</wicri:regionArea>
<wicri:noRegion>609-735</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Do Heo, Won" sort="Do Heo, Won" uniqKey="Do Heo W" first="Won" last="Do Heo">Won Do Heo</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jung, Jae U" sort="Jung, Jae U" uniqKey="Jung J" first="Jae U." last="Jung">Jae U. Jung</name>
<affiliation wicri:level="4"><nlm:aff id="aff003"><addr-line>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
<settlement type="city">Los Angeles</settlement>
</placeName>
<orgName type="university">Université de Californie du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Rigden, Daniel John" sort="Rigden, Daniel John" uniqKey="Rigden D" first="Daniel John" last="Rigden">Daniel John Rigden</name>
<affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Institute of Integrative Biology, University of Liverpool, Crown St., Liverpool, L69 7ZB, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Integrative Biology, University of Liverpool, Crown St., Liverpool, L69 7ZB</wicri:regionArea>
<wicri:noRegion>L69 7ZB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oh, Byung Ha" sort="Oh, Byung Ha" uniqKey="Oh B" first="Byung-Ha" last="Oh">Byung-Ha Oh</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">25821953</idno>
<idno type="pmc">4379102</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4379102</idno>
<idno type="RBID">PMC:4379102</idno>
<idno type="doi">10.1371/journal.pone.0118683</idno>
<date when="2015">2015</date>
<idno type="wicri:Area/Pmc/Corpus">000026</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000026</idno>
<idno type="wicri:Area/Pmc/Curation">000026</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000026</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000073</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000073</idno>
<idno type="wicri:Area/Ncbi/Merge">000377</idno>
<idno type="wicri:Area/Ncbi/Curation">000377</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000377</idno>
<idno type="wicri:Area/Main/Merge">000080</idno>
<idno type="wicri:Area/Main/Curation">000080</idno>
<idno type="wicri:Area/Main/Exploration">000080</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Lpg0393 of <italic>Legionella pneumophila</italic>
Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22</title>
<author><name sortKey="Sohn, Young Sik" sort="Sohn, Young Sik" uniqKey="Sohn Y" first="Young-Sik" last="Sohn">Young-Sik Sohn</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shin, Ho Chul" sort="Shin, Ho Chul" uniqKey="Shin H" first="Ho-Chul" last="Shin">Ho-Chul Shin</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="aff002"><addr-line>Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-600, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Medical Proteomics Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, 305-600</wicri:regionArea>
<wicri:noRegion>305-600</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Park, Wei Sun" sort="Park, Wei Sun" uniqKey="Park W" first="Wei Sun" last="Park">Wei Sun Park</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Ge, Jianning" sort="Ge, Jianning" uniqKey="Ge J" first="Jianning" last="Ge">Jianning Ge</name>
<affiliation wicri:level="4"><nlm:aff id="aff003"><addr-line>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
<settlement type="city">Los Angeles</settlement>
</placeName>
<orgName type="university">Université de Californie du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Kim, Chan Hee" sort="Kim, Chan Hee" uniqKey="Kim C" first="Chan-Hee" last="Kim">Chan-Hee Kim</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735</wicri:regionArea>
<wicri:noRegion>609-735</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lee, Bok Luel" sort="Lee, Bok Luel" uniqKey="Lee B" first="Bok Luel" last="Lee">Bok Luel Lee</name>
<affiliation wicri:level="1"><nlm:aff id="aff004"><addr-line>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Global Research Laboratory of Insect Symbiosis, College of Pharmacy, Pusan National University, Jangjeon Dong, Kumjeong Ku, Busan, 609-735</wicri:regionArea>
<wicri:noRegion>609-735</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Do Heo, Won" sort="Do Heo, Won" uniqKey="Do Heo W" first="Won" last="Do Heo">Won Do Heo</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Jung, Jae U" sort="Jung, Jae U" uniqKey="Jung J" first="Jae U." last="Jung">Jae U. Jung</name>
<affiliation wicri:level="4"><nlm:aff id="aff003"><addr-line>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America</addr-line>
</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California</wicri:regionArea>
<placeName><region type="state">Californie</region>
<settlement type="city">Los Angeles</settlement>
</placeName>
<orgName type="university">Université de Californie du Sud</orgName>
</affiliation>
</author>
<author><name sortKey="Rigden, Daniel John" sort="Rigden, Daniel John" uniqKey="Rigden D" first="Daniel John" last="Rigden">Daniel John Rigden</name>
<affiliation wicri:level="1"><nlm:aff id="aff005"><addr-line>Institute of Integrative Biology, University of Liverpool, Crown St., Liverpool, L69 7ZB, United Kingdom</addr-line>
</nlm:aff>
<country xml:lang="fr">Royaume-Uni</country>
<wicri:regionArea>Institute of Integrative Biology, University of Liverpool, Crown St., Liverpool, L69 7ZB</wicri:regionArea>
<wicri:noRegion>L69 7ZB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Oh, Byung Ha" sort="Oh, Byung Ha" uniqKey="Oh B" first="Byung-Ha" last="Oh">Byung-Ha Oh</name>
<affiliation wicri:level="1"><nlm:aff id="aff001"><addr-line>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>Department of Biological Sciences, KAIST Institute for the Biocentury, Cancer Metastasis Control Center, Korea Advanced Institute of Science and Technology, Daejeon, 305-701</wicri:regionArea>
<wicri:noRegion>305-701</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS ONE</title>
<idno type="eISSN">1932-6203</idno>
<imprint><date when="2015">2015</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p><italic>Legionella pneumophila</italic>
, a human intracellular pathogen, encodes about 290 effector proteins that are translocated into host cells through a secretion machinery. Some of these proteins have been shown to manipulate or subvert cellular processes during infection, but functional roles of a majority of them remain unknown. Lpg0393 is a newly identified <italic>Legionella</italic>
effector classified as a hypothetical protein. Through X-ray crystallographic analysis, we show that Lpg0393 contains a Vps9-like domain, which is structurally most similar to the catalytic core of human Rabex-5 that activates the endosomal Rab proteins Rab5, Rab21 and Rab22. Consistently, Lpg0393 exhibited a guanine-nucleotide exchange factor activity toward the endosomal Rabs. This work identifies the first example of a bacterial guanine-nucleotide exchange factor that is active towards the Rab5 sub-cluster members, implying that the activation of these Rab proteins might be advantageous for the intracellular survival of <italic>Legionella</italic>
.</p>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Kagan, Jc" uniqKey="Kagan J">JC Kagan</name>
</author>
<author><name sortKey="Stein, Mp" uniqKey="Stein M">MP Stein</name>
</author>
<author><name sortKey="Pypaert, M" uniqKey="Pypaert M">M Pypaert</name>
</author>
<author><name sortKey="Roy, Cr" uniqKey="Roy C">CR Roy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Xu, L" uniqKey="Xu L">L Xu</name>
</author>
<author><name sortKey="Luo, Zq" uniqKey="Luo Z">ZQ Luo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tilney, Lg" uniqKey="Tilney L">LG Tilney</name>
</author>
<author><name sortKey="Harb, Os" uniqKey="Harb O">OS Harb</name>
</author>
<author><name sortKey="Connelly, Ps" uniqKey="Connelly P">PS Connelly</name>
</author>
<author><name sortKey="Robinson, Cg" uniqKey="Robinson C">CG Robinson</name>
</author>
<author><name sortKey="Roy, Cr" uniqKey="Roy C">CR Roy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Vogel, Jp" uniqKey="Vogel J">JP Vogel</name>
</author>
<author><name sortKey="Andrews, Hl" uniqKey="Andrews H">HL Andrews</name>
</author>
<author><name sortKey="Wong, Sk" uniqKey="Wong S">SK Wong</name>
</author>
<author><name sortKey="Isberg, Rr" uniqKey="Isberg R">RR Isberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Segal, G" uniqKey="Segal G">G Segal</name>
</author>
<author><name sortKey="Purcell, M" uniqKey="Purcell M">M Purcell</name>
</author>
<author><name sortKey="Shuman, Ha" uniqKey="Shuman H">HA Shuman</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Machner, Mp" uniqKey="Machner M">MP Machner</name>
</author>
<author><name sortKey="Isberg, Rr" uniqKey="Isberg R">RR Isberg</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Murata, T" uniqKey="Murata T">T Murata</name>
</author>
<author><name sortKey="Delprato, A" uniqKey="Delprato A">A Delprato</name>
</author>
<author><name sortKey="Ingmundson, A" uniqKey="Ingmundson A">A Ingmundson</name>
</author>
<author><name sortKey="Toomre, Dk" uniqKey="Toomre D">DK Toomre</name>
</author>
<author><name sortKey="Lambright, Dg" uniqKey="Lambright D">DG Lambright</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Muller, Mp" uniqKey="Muller M">MP Muller</name>
</author>
<author><name sortKey="Peters, H" uniqKey="Peters H">H Peters</name>
</author>
<author><name sortKey="Blumer, J" uniqKey="Blumer J">J Blumer</name>
</author>
<author><name sortKey="Blankenfeldt, W" uniqKey="Blankenfeldt W">W Blankenfeldt</name>
</author>
<author><name sortKey="Goody, Rs" uniqKey="Goody R">RS Goody</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ingmundson, A" uniqKey="Ingmundson A">A Ingmundson</name>
</author>
<author><name sortKey="Delprato, A" uniqKey="Delprato A">A Delprato</name>
</author>
<author><name sortKey="Lambright, Dg" uniqKey="Lambright D">DG Lambright</name>
</author>
<author><name sortKey="Roy, Cr" uniqKey="Roy C">CR Roy</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mukherjee, S" uniqKey="Mukherjee S">S Mukherjee</name>
</author>
<author><name sortKey="Liu, X" uniqKey="Liu X">X Liu</name>
</author>
<author><name sortKey="Arasaki, K" uniqKey="Arasaki K">K Arasaki</name>
</author>
<author><name sortKey="Mcdonough, J" uniqKey="Mcdonough J">J McDonough</name>
</author>
<author><name sortKey="Galan, Je" uniqKey="Galan J">JE Galan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tan, Y" uniqKey="Tan Y">Y Tan</name>
</author>
<author><name sortKey="Arnold, Rj" uniqKey="Arnold R">RJ Arnold</name>
</author>
<author><name sortKey="Luo, Zq" uniqKey="Luo Z">ZQ Luo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Schoebel, S" uniqKey="Schoebel S">S Schoebel</name>
</author>
<author><name sortKey="Cichy, Al" uniqKey="Cichy A">AL Cichy</name>
</author>
<author><name sortKey="Goody, Rs" uniqKey="Goody R">RS Goody</name>
</author>
<author><name sortKey="Itzen, A" uniqKey="Itzen A">A Itzen</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Neunuebel, Mr" uniqKey="Neunuebel M">MR Neunuebel</name>
</author>
<author><name sortKey="Mohammadi, S" uniqKey="Mohammadi S">S Mohammadi</name>
</author>
<author><name sortKey="Jarnik, M" uniqKey="Jarnik M">M Jarnik</name>
</author>
<author><name sortKey="Machner, Mp" uniqKey="Machner M">MP Machner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Tan, Y" uniqKey="Tan Y">Y Tan</name>
</author>
<author><name sortKey="Luo, Zq" uniqKey="Luo Z">ZQ Luo</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Ku, B" uniqKey="Ku B">B Ku</name>
</author>
<author><name sortKey="Lee, Kh" uniqKey="Lee K">KH Lee</name>
</author>
<author><name sortKey="Park, Ws" uniqKey="Park W">WS Park</name>
</author>
<author><name sortKey="Yang, Cs" uniqKey="Yang C">CS Yang</name>
</author>
<author><name sortKey="Ge, J" uniqKey="Ge J">J Ge</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gaspar, Ah" uniqKey="Gaspar A">AH Gaspar</name>
</author>
<author><name sortKey="Machner, Mp" uniqKey="Machner M">MP Machner</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hoffmann, C" uniqKey="Hoffmann C">C Hoffmann</name>
</author>
<author><name sortKey="Finsel, I" uniqKey="Finsel I">I Finsel</name>
</author>
<author><name sortKey="Otto, A" uniqKey="Otto A">A Otto</name>
</author>
<author><name sortKey="Pfaffinger, G" uniqKey="Pfaffinger G">G Pfaffinger</name>
</author>
<author><name sortKey="Rothmeier, E" uniqKey="Rothmeier E">E Rothmeier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lifshitz, Z" uniqKey="Lifshitz Z">Z Lifshitz</name>
</author>
<author><name sortKey="Burstein, D" uniqKey="Burstein D">D Burstein</name>
</author>
<author><name sortKey="Peeri, M" uniqKey="Peeri M">M Peeri</name>
</author>
<author><name sortKey="Zusman, T" uniqKey="Zusman T">T Zusman</name>
</author>
<author><name sortKey="Schwartz, K" uniqKey="Schwartz K">K Schwartz</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rigden, Dj" uniqKey="Rigden D">DJ Rigden</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Soding, J" uniqKey="Soding J">J Soding</name>
</author>
<author><name sortKey="Biegert, A" uniqKey="Biegert A">A Biegert</name>
</author>
<author><name sortKey="Lupas, An" uniqKey="Lupas A">AN Lupas</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Delprato, A" uniqKey="Delprato A">A Delprato</name>
</author>
<author><name sortKey="Lambright, Dg" uniqKey="Lambright D">DG Lambright</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Uejima, T" uniqKey="Uejima T">T Uejima</name>
</author>
<author><name sortKey="Ihara, K" uniqKey="Ihara K">K Ihara</name>
</author>
<author><name sortKey="Goh, T" uniqKey="Goh T">T Goh</name>
</author>
<author><name sortKey="Ito, E" uniqKey="Ito E">E Ito</name>
</author>
<author><name sortKey="Sunada, M" uniqKey="Sunada M">M Sunada</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Holm, L" uniqKey="Holm L">L Holm</name>
</author>
<author><name sortKey="Rosenstrom, P" uniqKey="Rosenstrom P">P Rosenstrom</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Delprato, A" uniqKey="Delprato A">A Delprato</name>
</author>
<author><name sortKey="Merithew, E" uniqKey="Merithew E">E Merithew</name>
</author>
<author><name sortKey="Lambright, Dg" uniqKey="Lambright D">DG Lambright</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Itzen, A" uniqKey="Itzen A">A Itzen</name>
</author>
<author><name sortKey="Rak, A" uniqKey="Rak A">A Rak</name>
</author>
<author><name sortKey="Goody, Rs" uniqKey="Goody R">RS Goody</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Esters, H" uniqKey="Esters H">H Esters</name>
</author>
<author><name sortKey="Alexandrov, K" uniqKey="Alexandrov K">K Alexandrov</name>
</author>
<author><name sortKey="Iakovenko, A" uniqKey="Iakovenko A">A Iakovenko</name>
</author>
<author><name sortKey="Ivanova, T" uniqKey="Ivanova T">T Ivanova</name>
</author>
<author><name sortKey="Thoma, N" uniqKey="Thoma N">N Thoma</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Suh, Hy" uniqKey="Suh H">HY Suh</name>
</author>
<author><name sortKey="Lee, Dw" uniqKey="Lee D">DW Lee</name>
</author>
<author><name sortKey="Lee, Kh" uniqKey="Lee K">KH Lee</name>
</author>
<author><name sortKey="Ku, B" uniqKey="Ku B">B Ku</name>
</author>
<author><name sortKey="Choi, Sj" uniqKey="Choi S">SJ Choi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Galperin, E" uniqKey="Galperin E">E Galperin</name>
</author>
<author><name sortKey="Sorkin, A" uniqKey="Sorkin A">A Sorkin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hutagalung, Ah" uniqKey="Hutagalung A">AH Hutagalung</name>
</author>
<author><name sortKey="Novick, Pj" uniqKey="Novick P">PJ Novick</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Zhu, H" uniqKey="Zhu H">H Zhu</name>
</author>
<author><name sortKey="Zhu, G" uniqKey="Zhu G">G Zhu</name>
</author>
<author><name sortKey="Liu, J" uniqKey="Liu J">J Liu</name>
</author>
<author><name sortKey="Liang, Z" uniqKey="Liang Z">Z Liang</name>
</author>
<author><name sortKey="Zhang, Xc" uniqKey="Zhang X">XC Zhang</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Goud, B" uniqKey="Goud B">B Goud</name>
</author>
<author><name sortKey="Zahraoui, A" uniqKey="Zahraoui A">A Zahraoui</name>
</author>
<author><name sortKey="Tavitian, A" uniqKey="Tavitian A">A Tavitian</name>
</author>
<author><name sortKey="Saraste, J" uniqKey="Saraste J">J Saraste</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Stein, M" uniqKey="Stein M">M Stein</name>
</author>
<author><name sortKey="Pilli, M" uniqKey="Pilli M">M Pilli</name>
</author>
<author><name sortKey="Bernauer, S" uniqKey="Bernauer S">S Bernauer</name>
</author>
<author><name sortKey="Habermann, Bh" uniqKey="Habermann B">BH Habermann</name>
</author>
<author><name sortKey="Zerial, M" uniqKey="Zerial M">M Zerial</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Lucas, M" uniqKey="Lucas M">M Lucas</name>
</author>
<author><name sortKey="Gaspar, Ah" uniqKey="Gaspar A">AH Gaspar</name>
</author>
<author><name sortKey="Pallara, C" uniqKey="Pallara C">C Pallara</name>
</author>
<author><name sortKey="Rojas, Al" uniqKey="Rojas A">AL Rojas</name>
</author>
<author><name sortKey="Fernandez Recio, J" uniqKey="Fernandez Recio J">J Fernandez-Recio</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Waterhouse, Am" uniqKey="Waterhouse A">AM Waterhouse</name>
</author>
<author><name sortKey="Procter, Jb" uniqKey="Procter J">JB Procter</name>
</author>
<author><name sortKey="Martin, Dm" uniqKey="Martin D">DM Martin</name>
</author>
<author><name sortKey="Clamp, M" uniqKey="Clamp M">M Clamp</name>
</author>
<author><name sortKey="Barton, Gj" uniqKey="Barton G">GJ Barton</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Katoh, K" uniqKey="Katoh K">K Katoh</name>
</author>
<author><name sortKey="Standley, Dm" uniqKey="Standley D">DM Standley</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Shen, A" uniqKey="Shen A">A Shen</name>
</author>
<author><name sortKey="Lupardus, Pj" uniqKey="Lupardus P">PJ Lupardus</name>
</author>
<author><name sortKey="Morell, M" uniqKey="Morell M">M Morell</name>
</author>
<author><name sortKey="Ponder, El" uniqKey="Ponder E">EL Ponder</name>
</author>
<author><name sortKey="Sadaghiani, Am" uniqKey="Sadaghiani A">AM Sadaghiani</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Otwinowski, Z" uniqKey="Otwinowski Z">Z Otwinowski</name>
</author>
<author><name sortKey="Minor, W" uniqKey="Minor W">W Minor</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Adams, Pd" uniqKey="Adams P">PD Adams</name>
</author>
<author><name sortKey="Mustyakimov, M" uniqKey="Mustyakimov M">M Mustyakimov</name>
</author>
<author><name sortKey="Afonine, Pv" uniqKey="Afonine P">PV Afonine</name>
</author>
<author><name sortKey="Langan, P" uniqKey="Langan P">P Langan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Emsley, P" uniqKey="Emsley P">P Emsley</name>
</author>
<author><name sortKey="Lohkamp, B" uniqKey="Lohkamp B">B Lohkamp</name>
</author>
<author><name sortKey="Scott, Wg" uniqKey="Scott W">WG Scott</name>
</author>
<author><name sortKey="Cowtan, K" uniqKey="Cowtan K">K Cowtan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brunger, At" uniqKey="Brunger A">AT Brunger</name>
</author>
<author><name sortKey="Adams, Pd" uniqKey="Adams P">PD Adams</name>
</author>
<author><name sortKey="Clore, Gm" uniqKey="Clore G">GM Clore</name>
</author>
<author><name sortKey="Delano, Wl" uniqKey="Delano W">WL DeLano</name>
</author>
<author><name sortKey="Gros, P" uniqKey="Gros P">P Gros</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Corée du Sud</li>
<li>Royaume-Uni</li>
<li>États-Unis</li>
</country>
<region><li>Californie</li>
</region>
<settlement><li>Los Angeles</li>
</settlement>
<orgName><li>Université de Californie du Sud</li>
</orgName>
</list>
<tree><country name="Corée du Sud"><noRegion><name sortKey="Sohn, Young Sik" sort="Sohn, Young Sik" uniqKey="Sohn Y" first="Young-Sik" last="Sohn">Young-Sik Sohn</name>
</noRegion>
<name sortKey="Do Heo, Won" sort="Do Heo, Won" uniqKey="Do Heo W" first="Won" last="Do Heo">Won Do Heo</name>
<name sortKey="Kim, Chan Hee" sort="Kim, Chan Hee" uniqKey="Kim C" first="Chan-Hee" last="Kim">Chan-Hee Kim</name>
<name sortKey="Lee, Bok Luel" sort="Lee, Bok Luel" uniqKey="Lee B" first="Bok Luel" last="Lee">Bok Luel Lee</name>
<name sortKey="Oh, Byung Ha" sort="Oh, Byung Ha" uniqKey="Oh B" first="Byung-Ha" last="Oh">Byung-Ha Oh</name>
<name sortKey="Park, Wei Sun" sort="Park, Wei Sun" uniqKey="Park W" first="Wei Sun" last="Park">Wei Sun Park</name>
<name sortKey="Shin, Ho Chul" sort="Shin, Ho Chul" uniqKey="Shin H" first="Ho-Chul" last="Shin">Ho-Chul Shin</name>
<name sortKey="Shin, Ho Chul" sort="Shin, Ho Chul" uniqKey="Shin H" first="Ho-Chul" last="Shin">Ho-Chul Shin</name>
</country>
<country name="États-Unis"><region name="Californie"><name sortKey="Ge, Jianning" sort="Ge, Jianning" uniqKey="Ge J" first="Jianning" last="Ge">Jianning Ge</name>
</region>
<name sortKey="Jung, Jae U" sort="Jung, Jae U" uniqKey="Jung J" first="Jae U." last="Jung">Jae U. Jung</name>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Rigden, Daniel John" sort="Rigden, Daniel John" uniqKey="Rigden D" first="Daniel John" last="Rigden">Daniel John Rigden</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Terre/explor/CobaltMaghrebV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000080 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000080 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Terre |area= CobaltMaghrebV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:4379102 |texte= Lpg0393 of Legionella pneumophila Is a Guanine-Nucleotide Exchange Factor for Rab5, Rab21 and Rab22 }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:25821953" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a CobaltMaghrebV1
This area was generated with Dilib version V0.6.32. |